Introduction: Cavernous hemangioma accounts for 0.6% of bladder tumors. We present a rare case Case Presentation: A 3-year-old girl presented with intravaginal swelling, dysuria, and hematuria. She received 26 cycles of VAC for embryonal rhabdomyosarcoma. Histopathology confirmed CH. Conclusion: CH should be considered in the differentials of childhood genitourinary masses.

Background: Trisomy 17 is a rare chromosomal disorder with limited existing literature that mostly refer to mosaic Trisomy 17 cases. Our report summarizes the clinical course of a neonate with a Trisomy 17 karyotype der (14;17) (q10; p10), + 17 pat. Key words: Trisomy 17, Unbalanced translocation, Paternal origin

Water inside plants forms a continuous chain from water in soils to the water evaporating from leaf surfaces. Failures in this chain result in reduced transpiration and photosynthesis and these failures are caused by soil drying and/or cavitation-induced xylem embolism. Xylem embolism and plant hydraulic failure share a number of analogies to “catastrophe theory” in dynamical systems. These catastrophes are often represented in the physiological and ecological literature as tipping points or alternative stable states when control variables exogenous (e.g. soil water potential) or endogenous (e.g. leaf water potential) to the plant are allowed to slowly vary. Here, plant hydraulics viewed from the perspective of catastrophes at multiple spatial scales is considered with attention to bubble expansion (i.e. cavitation), organ-scale vulnerability to embolism, and whole-plant biomass as a proxy for transpiration and hydraulic function. The hydraulic safety-efficiency tradeoff, hydraulic segmentation and maximum plant transpiration are examined using this framework. Underlying mechanisms for hydraulic failure at very fine scales such as pit membranes, intermediate scales such as xylem network properties and at larger scales such as soil-tree hydraulic pathways are discussed. Lacunarity areas in plant hydraulics are also flagged where progress is urgently needed.

Understanding the structure and connectivity of coral populations is fundamental for developing marine conservation policies, especially in patchy environments such as archipelagos. The Nansei Islands, extending more than 1,000 km in southwestern Japan, are characterized by high levels of biodiversity and endemism, supported by coral reefs, although precise, detailed genetic attributes of corals are still largely unknown. In this study, we conducted population genomic analyses based on genome-wide, single-nucleotide polymorphisms (SNPs) of Acropora digitifera, a common species in the Nansei Islands, for which a complete genome is available. With ~24x sequencing coverage of entire genomes of 303 colonies collected at 21 locations, we identified more than four million genome-wide SNPs. While population structure analyses suggested weak genetic differentiation among sampled locations, the most southwestern location (the west end of the Yaeyama Islands) was genetically similar to the northernmost location (the Tanegashima Islands), separated by >1,000 km. Although examination of a migration network found a general tendency of northward migration along the Kuroshio Current, a substantial amount of southward migration was also detected, indicating important contributions of minor ocean currents to coral larval dispersal. Moreover, heterogeneity in the transition of effective population sizes among locations suggests different histories for individual subpopulations. The unexpected complexity of both past and present population dynamics in the Nansei Islands implies that heterogeneity of ocean currents and local environments, past and present, have influenced the population structure of this species, highlighting the importance of local scale assessments for effective coral restoration and management.

A multilayer overlay coating system containing an intermediate intermetallic layer (designated 2IML) is an architecture expected to show good fatigue resistance. Experimental characterisation and modelling simulations were carried out to classify the different crack initiation mechanisms occurring during fatigue of this coating system and to reveal how changes in the layer architecture lead to fatigue improvement. Fatigue improvement is achieved by decreasing the IML-Top layer thickness due to the increased surface crack initiation resistance. However subsurface initiation mechanisms inhibit the improvement (dominated by surface initiation mechanism) achieved by locating the IML-Top layer closer to the top surface.

In recent years, a number of monogenic disorders have been described that are characterized by immune dysregulation. A subset of these ‘primary immune regulatory disorders’ can cause severe interstitial lung disease, often recognized in late childhood or adolescence. Patients presenting to pulmonary clinic may have long and complex medical histories but lack a unifying genetic diagnosis. It is crucial for pulmonologists to recognize features suggestive of multisystem immune dysregulation and to initiate genetic workup, since targeted therapies based on underlying genetics may halt or even reverese pulmonary disease progression. Through such an approach, our center has been able to diagnose and treat a cohort of patients with interstitial lung disease from gene defects that affect immune regulation. Here we present representative cases related to pathogenic mutations in three distinct pathways and summarize disease manifestations and treatment approaches. We conclude with a discussion of our perspective on the outstanding challenges for diagnosing and managing these complex life-threatening and chronic disorders.

The rare disseminated form of Herpes Zoster occurred mainly in immunocompromised patients. We hereby, present the first case of atypical disseminated herpes zoster in a 54-year old woman admitted with serious COVID. This case serves as a reminder for considering atypical presentations of cutaneous disorders in immunocompromised patients.

Previous studies reported that several amino acids had strong antioxidant activity in vegetable oils under frying conditions. In this study, the carboxylic acid group of amino acids was converted to a carboxylate group (-COO-Na+ or -COO-K+), a heating study was conducted with amino acid salts in soybean oil at 180 ºC. Sodium salts of amino acids including alanine, phenylalanine, and proline and disodium glutamate had significantly stronger antioxidant activity than the corresponding amino acids, and potassium salts had stronger antioxidant activity than sodium salts. Potassium salts of alanine and phenylalanine more effectively retained tocopherols in soybean oil than the corresponding amino acids during heating. Phenylalanine potassium salt had stronger antioxidant activity than phenylalanine in other vegetable oils including olive, high oleic soybean, canola, avocado, and corn oils. Phenylalanine potassium salt at 5.5. mM more effectively prevented oil oxidation than tert-butyl hydroquinone (TBHQ), a synthetic antioxidant, at its legal concentration limit (0.02%) indicating its feasibility as a new antioxidant for frying.

In this paper we study the null controllability for the problems associated to the operators y_t-Ay - \lambda/b(x) y+\int_0^1 K(t,x,\tau)y(t, \tau) d\tau, (t,x) \in (0,T)\times (0,1) where Ay := ay_{xx} or Ay := (ay_x)_x and the functions a and b degenerate at an interior point x0 Ë .0; 1/. To this aim, as a first step we study the well posedness, the Carleman estimates and the null controllability for the associated nonhomogeneous degenerate and singular heat equations. Then,using the Kakutani’s fixed point Theorem, we deduce the null controllability property for the initial nonlocal problems.

Petroleum based plastics are durable and accumulate in all ecological niches. Knowledge on enzymatic degradation is sparse. Today, less than 50 verified plastics-active enzymes are known. First examples of enzymes acting on the polymers polyethylene terephthalate (PET) and polyurethane (PUR) have been reported together with a detailed biochemical and structural description. Further, very few polyamide (PA) oligomer active enzymes are known. In this paper, the current known enzymes acting on the synthetic polymers PET and PUR are briefly summarized, their published activity data were collected and integrated into a comprehensive open access database. The Plastics-Active Enzymes Database (PAZy) represents an inventory of known and experimentally verified plastics-active enzymes. Almost 3000 homologues of PET-active enzymes were identified by profile hidden Markov models. Over 2000 homologues of PUR-active enzymes were identified by BLAST. Based on multiple sequence alignments, conservation analysis identified the most conserved amino acids, and sequence motifs for PET- and PUR-active enzymes were derived.

In the present paper, we study a class of quasilinear Choquard equations involving N-Laplacian and the nonlinearity with the critical exponential growth. We discuss the existence of positive solutions of such equations.

Primary failure of eruption is characterized by a non-syndromic eruption failure of permanent teeth in the absence of any mechanical obstruction. Applying orthodontic traction to teeth affected by PFE will not be successful and may cause ankylosis. This correspondence reviews and demonstrates the treatment of a case of PFE.

In heterotaxy syndrome, bronchopulmonary situs usually reflects atrial situs, resulting in either right (RAI) or left atrial isomerism (LAI). This study determines airway anomalies and its implications in patients with heterotaxy. This retrospective study included 223 patients with heterotaxy syndrome who received an integrated cardiac computed tomography evaluation. Patient database from 1995 to 2020 was reviewed. The patients were examined by a congenital heart disease team comprising pediatric cardiologists, radiologists, pulmonologists, and cardiovascular surgeons. Among the 223 patients, 189 (84.8%, M/F=1.66) had RAI and 29 had LAI (13.0%, M/F=0.71). Five patients had indeterminate isomerism (2.2%, M/F=1.5). Discordant bronchopulmonary and atrial situs occurred in 4% patients, while discordant bronchopulmonary, atrial, and splenic situs occurred in 23.2% patients. Lower airway stenosis was observed in 61 patients (27.4%), including 27.5%, 20.7%, and 60% RAI, LAI, and indeterminate isomerism patients, respectively (p=0.189). One patient had an intrinsic long segment lower tracheal stenosis and received slide tracheoplasty. Initial cardiac operation was performed in 213 patients. Higher surgical mortality occurred in patients with RAI (19.5% vs. none for LAI and indeterminate isomerism, p=0.038). In patients with RAI, lower airway anomaly/stenosis increased the duration of ventilator usage (p=0.030) but did not affect surgical mortality. Total anomalous pulmonary venous return to systemic veins and pulmonary venous stenosis were major surgical risk factors. Bronchopulmonary isomerism shares a similar isomeric pattern to cardiac atrial appendage. Lower airway anomalies/stenosis was common in patients with heterotaxy, resulting in prolonged ventilator therapy in patients with RAI.

The purpose of this work is to investigate perfect reconstruction underlying range space of operators in finite dimensional Hilbert spaces by a new matrix method. To this end, first we obtain more structures of the canonical $K$-dual. % and survey optimal $K$-dual problem under probabilistic erasures. Then, we survey the problem of recovering and robustness of signals when the erasure set satisfies the minimal redundancy condition or the $K$-frame is maximal robust. Furthermore, we show that the error rate is reduced under erasures if the $K$-frame is of uniform excess. Toward the protection of encoding frame (K-dual) against erasures, we introduce a new concept so called $(r,k)$-matrix to recover lost data and solve the perfect recovery problem via matrix equations. Moreover, we discuss the existence of such matrices by using minimal redundancy condition on decoding frames for operators. We exhibit several examples that illustrate the advantage of using the new matrix method with respect to the previous approaches in existence construction. And finally, we provide the numerical results to confirm the main results in the case noise-free and test sensitivity of the method with respect to noise.

The problem of farmland degradation and air pollution caused by wind erosion and particulate matter emissions is serious. Relying on biological soil crust coverage can effectively inhibit the production of wind erosion materials. However, recent studies have discussed the wind erosion and particulate matter emission processes separately and few studies analyzed both, clarifying the changes in the proportion of particulate matter emissions in the total wind erosion. Aiming at the typical farming-pastoral transition zone in the monsoon climate zone, this study used wind tunnels to analyze the wind erosion and particulate matter emissions of algae crusts and moss crusts for different wind speeds and coverage conditions. Results show that the effects of wind speed and coverage on the total wind erosion of biological soil crusts are similar. However, the emission of particulate matter is particularly sensitive to coverage of biological soil crusts. The proportion of particulate matter emissions in wind erosion decreases with increasing wind speed. According to the trend of the proportion with wind speed, the particle emission capacity of moss crust is directly proportional to the particle size and inversely proportional to the coverage. In contrast, the particle emission capacity of algae crust particles is proportional to the particle size, but the relationship with coverage is not regular. The results of this study can improve the knowledge of the relationship between wind erosion and particulate matter emissions and give relevant information for the management of wind erosion and particulate matter emissions.

Background: Insertable cardiac monitors (ICMs) are essential for ambulatory arrhythmia diagnosis. However, definitive diagnoses still require time-consuming, manual adjudication of electrograms (EGMs). Objective: To evaluate the clinical impact of selecting only key EGMs for review. Methods: Retrospective analyses of randomly selected Abbott Confirm Rx TM devices with ≥90 days of remote transmission history was performed, with each EGM adjudicated as true or false positive (TP, FP). For each device, up to 3 “key EGMs” per arrhythmia type per day were prioritized for review based on ventricular rate and episode duration. The reduction in EGMs and TP days (patient-days with at least 1 TP EGM), and any diagnostic delay (from the first TP), were calculated vs. reviewing all EGMs. Results: In 1,000 ICMs over a median duration of 8.1 months, at least one atrial fibrillation (AF), tachycardia, bradycardia, or pause EGM was transmitted by 424, 343, 190, and 325 devices, respectively, with a total of 95716 EGMs. Approximately 90% of episodes were contributed by 25% of patients. Key EGM selection reduced EGM review burden by 43%, 66%, 77%, and 50% (55% overall), while reducing TP days by 0.8%, 2.1%, 0.2%, and 0.0%, respectively. Despite reviewing fewer EGMs, 99% of devices with a TP EGM were ultimately diagnosed on the same day vs. reviewing all EGMs. Conclusions: Key EGM selection reduced the EGM review substantially with no delay-to-diagnosis in 99% of patients exhibiting true arrhythmias. Implementing these rules in the Abbott patient care network may accelerate clinical workflow without compromising diagnostic timelines.

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Hysterosalpingography (HSG) is widely performed in combination with assisted reproductive technology, and the contrast medium used in this procedure may be retained in the pelvic cavity. In patients showing suspected operative-residue lesions after caesarean section, a medical history of HSG and details regarding abnormal findings can facilitate differential diagnosis.