Leveraging the ultra-wideband advantages of the Terahertz (THz) band, Integrated Sensing and Communication (ISAC) facilitates high-precision sensing demands in human smart home applications. ISAC channel characteristics are the basis for ISAC system design. Currently, the ISAC channel is divided into target and background channels. Existing researches primarily focus on the attributes of human target itself, e.g., radar cross-section and Micro-Doppler effect. However, the impact of human target on neither the pathloss characteristic of background channel nor the multipath propagation characteristic of target channel is considered. To address the gap, we conduct indoor channel measurements at 105 GHz to investigate the ISAC channel characteristics with the impact of human target. Firstly, by analyzing the power angular delay profiles with and without human target, we observe the changes in quantity and power of multipath components (MPCs). Then, we propose a parameter called power control factor (PCF) to evaluate the human target impact on pathloss, thereby modifying the existing pathloss model of background channel. Eventually, we extract the MPCs belonging to target channel within target-oriented power delay profile to count the power proportion of each bounce MPCs of the target-Rx link, which supports the necessity of multi-bounce (indirect) paths modeling in target channel.