Cyclostratigraphic analyses were performed on magnetic susceptibility (MS), and elemental Ti and Fe series along the upper Aptian-lower Albian interval of the Poggio le Guaine (PLG) core, a Cretaceous pelagic succession in the Umbria-Marche Basin (central Italy). This interval represents one the most detailed and complete sedimentary archives and records oceanic perturbations associated with Oceanic Anoxic Event (OAE) 1b. The MS, Ti and Fe orbital control indicates a timespan of 2.68 Myr for OAE 1b event (114.10 to 111.34 Ma) and short eccentricity cycles played a key role, in controlling the amount of detrital input from weathering during monsoonal periods. Our chronostratigraphic study also provides age of 114.09 Ma for 113/Jacob, 113.25 Ma for Kilian, 112.67 Ma as a central age of the Monte Nerone cluster, 111.70 Ma for Urbino and 111.37 Ma for Leenhardt subevents, and a timespan of ~20 kyr for 113/Jacob, 70 kyr for Kilian, 670 kyr for Monte Nerone cluster, 60 kyr for Urbino and 60 kyr for Leenhardt levels. This study provides compelling evidence of the enormous potential C-isotope stratigraphy as tie points for cyclostratigraphic studies and as a valuable way to evaluate diachronism of bioevents. The organic-rich levels encompassing OAE 1b event has particular characteristics resulting from the combination of warm climate triggered by volcanic CO2 input, heavy precipitation, intense weathering and rapid marine transgressions, which leads the oceanic-atmospheric perturbations, acting as amplifiers of orbital forcings paleoclimate changes, resulting in deoxygenation and carbon burial during OAE 1b.