Stillbirth and very early neonatal mortality by Robson 10-group
classification system: A cross-sectional registry of 80633 births from
16 hospitals in Benin, Malawi, Tanzania and Uganda
Abstract
Objective: To better understand underlying factors of
peripartum mortality we assessed variations in mortality by Robson
10-group classification. Design: Cross-sectional study.
Setting: Prospectively collected perinatal e-registry data from
16 hospitals in Benin, Malawi, Tanzania and Uganda. Population:
All women aged 13-49 who gave birth to a live or stillborn baby
>1000g between July 2021 and December 2022.
Methods: We compared peripartum mortality risk by Robson group
and calculated proportional contributions to mortality. We assessed
interactions between mortality and Caesarean sections using
multivariable logistic regression and post-estimations margins.
Main Outcome Measures: Peripartum mortality, defined as
intrapartum stillbirths and very early (≤24 hours after birth) neonatal
deaths. Results: We included 80 663 babies born to 78 085
women, of which 1 706 were intrapartum stillbirths and 617 very early
neonatal deaths. Peripartum mortality was 5.2% (Benin), 1.6% (Malawi),
1.1% (Tanzania), and 3.7% (Uganda). The largest contributor to
intrapartum stillbirths (27.8%) and very early neonatal deaths (23.3%)
was Robson group 3 (multipara with cephalic term singleton in
spontaneous labour) followed by group 10 (preterm birth). Intrapartum
stillbirth risk in breech presentation (groups 6 and 7) was 5.1% in
nullipara and 11.1% in multipara. A Caesarean section halved the odds
of peripartum mortality in breech presentation in primipara (0.46; 95%
CI 0.22-0.95). Conclusions: Our findings indicate a high share
of peripartum mortality in lower obstetric risk groups and high
mortality in breech deliveries and preterm births. This underscores the
need to intensify actions to improve labour management.