1. IntroductionCutaneous metastases occur in approximately 0.7–0.9% of all cancer patients.1 Cutaneous metastasis can cause symptoms such as exudates, bleeding, and pain, which remarkably reduce patient’s quality of life. Radiation therapy is one of the effective treatment methods for cutaneous metastasis.2,3 Recently, the “Quad Shot” regimen, comprising 2 days of twice-daily fractionation with a fraction size of 3.5–3.7 Gy (14.0–14.8 Gy per cycle) repeated at 3–6-week intervals for a total of three cycles, has been successfully adapted for palliative treatment of head and neck cancer.4,5 However, to the best of our knowledge, there is no reports of using the Quad Shot regimen for cutaneous metastasis.Herein, we report a case in which radiation therapy using the Quad Shot regimen was effective in the treatment of cutaneous metastasis from parotid gland cancer.