Global environmental science challenges in the limnological research and applications communities can only be advanced when harnessing the collective expertise and capabilities of the satellite remote sensing community and well-established in situ communities such as the Global Lake Ecological Observatory Network (GLEON). At first glance, the groups seem wildly divergent: GLEON is a grass-roots effort which has been active since 2005 and connects researchers and practitioners from around the world to ask and answer questions about lake ecosystems. Earth observing missions can take a decade to plan, build, and launch. NASA and ESA have different missions as space agencies: one primarily focused on exploration and basic research with a year-to-year appropriations cycle, while the other presents a long-term commitment to address societal needs through the Copernicus program Sentinel satellite series. The Surface Biology and Geology (SBG) mission is a future NASA satellite that will launch toward the end of this decade as part of the Earth Systems Observatory. Working together to advance the science of lake ecosystem response to climate change, each group brings different complementary strengths and assets to this societal challenge. Increasing access through open science and cloud computing are creating opportunities for better collaboration. We describe our strategy for international engagement between these groups – cultural and methodological differences aside – to derive new information, learn new insights, and expand the body of knowledge around these unique natural resources.