COVID-19 is a new pandemic caused by SARS-CoV-2 which has created a havoc worldwide. Within no time it prevailed throughout the world compelling all countries to take emergency measures to overcome the pandemic. To overcome the disease, there is still no vaccine developed, however, different drugs are under trial. So, the only strategy to overcome the deadly virus is to avoid each and every way of contact with the already infected patients. For the assurance of avoidance policy, different countries took different measures according to their circumstances. Developing countries are much more infected than the developed ones as they already lack in fulfilling many basic necessities of life including economy. Pakistan is one of those developing countries whose economy is badly hit by following the model strategies of developed countries. So, Pakistan introduced different strategies like smart lock down, tiger force, etc. Pakistan has faced the worst peak of pandemic latter than most of the countries, so, to walk with the world in all aspects, Government should put its best efforts in the health zone to overcome COVID-19 as soon as possible.

Abstract An ongoing novel highly contagious pneumonia outbreak started in Wuhan, which is sprawling capital of central china’s province, Hubei, at the late December 2019. World Health Organization on February 12, 2020 officially named this disease as Coronavirus Disease 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). The primary host of SARS-CoV-2 is linked with bat specie however; the intermediate host is still not clear. The COVID-19 spread rapidly across the world because of person-person transmission. The SARS-CoV-2 stimulates both the cellular and humoral immunity mediated by viral specific B and T cells. Cases of COVID-19 infection exhibit several clinical complications for example fever, tiredness and dry cough. Diagnosis are mostly depending on epidemiological characteristics, clinical manifestation, and few through the examination of auxiliary tissues. In this review, we have provided a brief introduction of SARS-CoV-2, pathogenesis, diagnosis, immune responses, and treatments and future perspectives.