IntroductionAngiomyofibroblastoma (AMFB) is a relatively recently described tumor in the expanding spectrum of benign mesenchymal tumors that predominantly arise in the lower genitalia of women. AMFB was first illustrated by Fletcher et al.1 as a benign soft tissue tumor of the vulvar region which should be distinguished from aggressive angiomyxoma in a series published in 1992. AMFB also occurs in men and can arise in the inguen, scrotum, spermatic cord, and bladder2. Only 23 cases of male AMF were reported in the English-language literature based on a review of PubMed data since 19923,4. In this article, we report a case of AMFB in a middle-aged male that arose in the para-vesical region. Salient histopathology, IHC, and genetic features contribute to the diagnosis of AFMB and surgical excision is curative. Our work has been documented according to the CARE guidelines.