The optimal vaccination strategy to control COVID-19
- Huaiyu Teng,
- Toshikazu Kuniya
Toshikazu Kuniya
Kobe Daigaku Daigakuin System Johogaku Kenkyuka
Author ProfileAbstract
Models of infectious disease dynamics suggest that treatment,
vaccination, and isolation are required for the control of infectious
diseases. Considering that vaccination is one of the most effective
methods to control infectious diseases, it is often not possible to
rapidly vaccinate all susceptible populations in the early stages of the
spread of infectious diseases due to the limitation of the number of
vaccines, insufficient medical personnel, or the slow progress of
vaccination efforts. Our simulation analysis by building an SVIWRD model
found that the degree of negative impact of infectious diseases shown
when young and old people were divided into two populations and
vaccinated at different rates was different.Therefore, for the current
problem of continued spread of COVID-19, we consider the infectious
disease dynamics model to achieve the goal of making the risk of
infection of COVID-19 lower by controlling the proportion of vaccination
of elderly and young people. In this paper, we divided young and old
people into two groups, established an SVIWRD model, performed
single-objective optimization using Pontryagin's maximum principle, and
used the Runge-Kutta method for numerical calculation and simulation, so
as to arrive at a certain vaccination ratio that plays the effect of
reduced negative impact of COVID-19.20 Jul 2024Submitted to Mathematical Methods in the Applied Sciences 22 Jul 2024Submission Checks Completed
22 Jul 2024Assigned to Editor
26 Jul 2024Review(s) Completed, Editorial Evaluation Pending
01 Aug 2024Reviewer(s) Assigned
19 Nov 2024Editorial Decision: Revise Major