Dansgaard-Oeschger (DO) events are a dominant mode of millennial-scale climate variability during the last glacial period with most pronounced impacts in the North Atlantic region. In Antarctica, they manifest primarily as a muted and phase-shifted temperature signal, but recent studies suggest an additional in-phase component. Here, we analyze the Southern Hemisphere (SH) response to spontaneous DO-type oscillations in a general circulation model. Compared to Greenland temperatures, the dominant Antarctic temperature mode is inverted and delayed by ~275 years, consistent with the bipolar seesaw mechanism. However, the leading SH atmospheric circulation mode varies synchronously with Greenland temperatures. It features zonally heterogeneous anomalies induced by Pacific Walker circulation and SH Hadley cell modulations, with patterns differing notably from the leading modes of interannual variability. Comparison of simulated δ18O with speleothems and ice cores indicates a good agreement in the tropics and SH mid-latitudes but some deviations in Antarctica which warrant further research.