Zn alloy stent has become a promising implantable cardiac patch stent. However, traditional Zn alloy stents not only easily induce neointimal hyperplasia, but also cannot improve reperfusion ischemia after myocardial infarction. Here, the Yb/Er/CeO ₂ coating grow on the surface of Zn substrate, which inhibits the release of Zn ²⁺ and enhances the proliferation of vascular endothelial cells. This layer improves re-endothelialization and avoiding restenosis. Yb/Er/CeO ₂ coating generates the transition from the valence band to conduction band under 980 nm excitation, which forms transfer energy of photo-induced electron-hole pairs. This transfer energy can catalyze H ₂O and O ₂ to generate a chemical link group, which accelerate the deposition rate of drug-eluting coating PLGA and increase the corrosion resistance of Zn stents. Particularly, the Yb/Er/CeO ₂ coating exhibits good catalytic ability for active oxygen species (ROS), which can effectively scavenge myocardial cells damage. Yb/Er/CeO ₂ nanoparticles layer (Nps) improve mitochondrial function and increases oxidative phosphorylation, which achieves anti-damage effects. Zn@Yb/Er/CeO ₂/PLGA can serve as an excellent myocardial patch scaffold for repairing damaged myocardial cells, which has promising applications in the treatment of cardiovascular diseases.