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Intra-arterial CECT of the Distal Forelimb in Jeju horses: Evaluating CE Factors
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  • Seyoung Lee,
  • Kwang-Yun Shin,
  • Kija Lee,
  • Jong-pil Seo
Seyoung Lee
Jeju National University
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Kwang-Yun Shin
Jeju Provincial Government
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Kija Lee
Kyungpook National University College of Veterinary Medicine
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Jong-pil Seo
Jeju National University

Corresponding Author:[email protected]

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Abstract

Background: Few studies have investigated the adequate contrast enhancement (CE) evaluation depending on concentration, volume, and rate of contrast media (CM) and the scan parameters in equine contrast enhanced computed tomography (CECT). Objectives: We investigated CE of the deep digital flexor tendon (DDFT) and arteries depending on voltage, concentration, volume, and rate of CM during intra-arterial CECT of equine distal forelimbs. Study design: This is a prospective study. Methods: Six horses underwent fifty-four CT scans. First, the CE of DDFT and arteries was evaluated depending on the voltage (80 or 120 kV) and CM concentration (150, 120, or 90 mg I/mL in 50 mL of CM). Second, CE of DDFT and vessels was evaluated depending on the CM volume (50, 100, or 150 mL) and administration rate (2, 4, or 6 mL/s) with a fixed iodine delivery rate (IDR) (300 or 180 mg I/s). Results: CE of DDFT significantly increased at 80 kV of voltage and 150 mg I/mL of CM concentration (Median: 29.65; IQR: 1.74; P < 0.05). CE of the DDFT positively correlated with CM concentration (P = 0.0004; r = 0.75). At 180 mg I/s of IDR, an increase in rate and volume (6 mL/s and 150 mL) led to low contrast attenuation in the medial and lateral palmar arteries (median and IQR: 985.93 and 71.8 Hounsfield units [HU] and 988.73 and 41.16 HU, respectively); the CE was sufficient to distinguish the artery from the adjacent structures. Main limitations: The number of animals was small for parametric statistical analysis. Conclusions: Our results suggest that a low CM concentration could yield sufficient CE of the DDFT and arteries with adjusted CT scanning parameters or volume and injection rate of CM.
05 Feb 2024Submitted to Equine Veterinary Journal
05 Feb 2024Submission Checks Completed
05 Feb 2024Assigned to Editor
05 Feb 2024Review(s) Completed, Editorial Evaluation Pending
05 Feb 2024Reviewer(s) Assigned
12 Mar 2024Editorial Decision: Revise Minor
15 Apr 2024Review(s) Completed, Editorial Evaluation Pending
04 Jun 2024Editorial Decision: Revise Minor
08 Jul 2024Submission Checks Completed
08 Jul 2024Assigned to Editor
10 Jul 2024Review(s) Completed, Editorial Evaluation Pending
30 Jul 2024Editorial Decision: Accept