Introduction:
A medical condition characterized by the congenital absence of skin,
predominantly affecting the lower extremities, blisters on both skin and
mucous membranes, and congenital absence and deformities in nails, has
been identified within a familial context(1). The inheritance pattern
aligns with a fully penetrant, autosomal dominant gene(1).
In 1966, Bart introduced Bart syndrome, a condition marked by the
simultaneous occurrence of congenital epidermolysis bullosa, localized
congenital absence of skin affecting the extremities, and the abnormal
shedding or dystrophy of nails(2). This syndrome is fascinating in the
medical field due to its more optimistic prognosis when contrasted with
other epidermolysis bullosa types(2). This type is known as Aplasia
cutis congenital type VI(3).
In this study, we have presented a case of a neonate with some disorders
that guide us to different diagnoses and syndromes, such as CHIME
syndrome and Barth syndrome, that have contributed.