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High Risk Abdominal Pediatric Paraganglioma: a Case Report
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  • Francois Poumeaud,
  • Mathilde Duval,
  • Marion Gambart,
  • Lawrence Dierickx,
  • Olivier Abbo,
  • Gregory Hangard,
  • Jérôme Doyen,
  • Marie Vidal,
  • Sebastien Aubert,
  • Fabienne Carillo,
  • Celine Mouly,
  • Julie Vial,
  • Anne Brouchet,
  • Anne Laprie
Francois Poumeaud
IUCT Oncopole
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Mathilde Duval
IUCT Oncopole
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Marion Gambart
Hopital des Enfants
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Lawrence Dierickx
IUCT Oncopole
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Olivier Abbo
Hopital des Enfants
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Gregory Hangard
IUCT Oncopole
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Jérôme Doyen
Centre Antoine Lacassagne
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Marie Vidal
Centre Antoine Lacassagne
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Sebastien Aubert
Université Lille 2 Droit et Santé Faculté de Médecine Henri Warembourg
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Fabienne Carillo
IUCT Oncopole
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Celine Mouly
IUCT Oncopole
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Julie Vial
IUCT Oncopole
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Anne Brouchet
IUCT Oncopole
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Anne Laprie
Institut Claudius Regaud

Corresponding Author:[email protected]

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Abstract

We report the case of a 14 y.o girl treated with radiotherapy for an abdominal paraganglioma - rare pediatric abdominal tumor - with macroscopic tumoral residue after initial surgery and bone metastasis at diagnosis. Irradiation of the tumoral residue and adjacent vertebral metastasis was decided in national committee, proton or photon based-irradiations were compared, before choosing helical tomotherapy photonic irradiation to better protect kidneys. Response at three months was mixed, with mild regression on the tumoral residue contrasting with bone progression. The patient is now under screening to enter a prospective phase II trial of peptide receptor radionuclide therapy (PPRT).