Coronavirus disease 2019 (COVID-19) is caused by infecting with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that was recognized in late December 2019 in Wuhan, China. As the infection spread and rapidly becomes a global pandemic, effective therapy is urgently needed against the new coronavirus due to the increased morbidity and mortality rates. Based on this aspect, several therapeutic options have been explored, one of which is corticosteroids. Though the application of corticosteroids in treating COVID-19 remains controversial, this review aimed to evaluate and describe the effectiveness and safety of corticosteroids in the management of COVID-19.