Asymmetric Hydrogenation of Phenanthridines with Chiral boranes
Guangyu Cui, Xiangqing Feng,* and Haifeng Du*
Chin. J. Chem.2023, 41, XXX—XXX. DOI:
10.1002/cjoc.202300XXX
A metal-free asymmetric hydrogenation of phenanthridines was
successfully accomplished by using a chiral monoene-derived borane as a
catalyst. A variety of optically active dihydrophenanthridines were
furnished in high yields with up to 93% ee. The bulky substituents at
one phenyl group was required to enhance the difference between the two
sides of the N-ring.