The influence of climate feedbacks on regional hydrological changes under warming is poorly understood. Here, a moist energy balance model (MEBM) with a Hadley Cell parameterization is used to isolate the influence of climate feedbacks on changes in zonal-mean precipitation-minus-evaporation (P-E) under greenhouse-gas forcing. It is shown that cloud feedbacks act to narrow bands of tropical P-E and increase P-E in the deep tropics. The surface-albedo feedback shifts the location of maximum tropical P-E and increases P-E in the polar regions. The intermodel spread in the P-E changes associated with feedbacks arises mainly from cloud feedbacks, with the lapse-rate and surface-albedo feedbacks playing important roles in the polar regions. The P-E change associated with cloud feedback locking in the MEBM is similar to that of a climate model with inactive cloud feedbacks. This work highlights the unique role that climate feedbacks play in causing deviations from the “wet-gets-wetter, dry-gets-drier” paradigm.