Flores et al, 1983 [1]
|
61/M
|
Skin lesions, mild splenomegaly, cervical, axillary, and inguinal
lymphadenopathy, fever, weakness, fatigue, and weight loss.
|
Abdominal Computed Tomography (CT) revealed retroperitoneal
lymphadenopathy.
|
-White Blood cell (WBC), 8,200/cu mm, 26% neutrophils, 12%
lymphocytes, 62% eosinophils;
-Biopsies of skin lesions, liver, and lymph nodes revealed caseating
granulomas with Langhans’ giant cells and eosinophils.
-A Ziehl-Neelsen (ZN) stain found acid-fast bacteria.
-A needle-aspirated bone marrow specimen showed eosinophil
infiltration
|
Isoniazid, Rifampin, Ethambutol, Streptomycin
|
The patient’s health improved quickly.
|
Gill et al, 1940 [8]
|
19/M
|
Sharp chest pain, dry cough, sweating, upper abdominal discomfort,
fever, and tachycardia.
|
Right-sided pleural effusion
|
- A chest fluid sample was cloudy and blood-stained, and a differential
count indicated 80% eosinophil polymorphonuclear leukocytes.
-Blood eosinophils 14 %
|
Laparotomy
|
The patient died eleven weeks after admission as his health
worsened.
|
Hsu et al, 2000 [14] |
66/F |
Chronic renal failure, bilateral neck
mass growth (1–3 cm) and malaise |
CT showed numerous lymphadenopathies
and substantial central necrosis on both neck sides. |
Peritoneal
eosinophilia (54–85%) and peripheral eosinophilia (7–12%), pus-like
material with unidentified non-fermentative Gram-negative bacilli in the
biopsy. |
Isoniazid, Rifampicin, Ethambutol, and Pyrazinamide |
About 2
weeks later, her peripheral and peritoneal fluid eosinophilia
subsided. |
Garg et al, 2017 [5]
|
68/F
|
Cough, fatigue, weight loss, skinny, and pale
|
A contrast-enhanced CT of the chest and abdomen showed enlarged
non-necrotic mediastinal lymph nodes with chronic liver disease
features.
|
-Neutrophils 41%, lymphocytes 27%, and eosinophils 32%.
-Needle-aspirated bone marrow and biopsies showed increased eosinophilic
-Endoscopic bronchial ultrasound-guided fine-needle aspiration of
mediastinal lymph nodes showed tubercular inflammation with
bacilli-positive acid-fast stain.
|
Isoniazid, Rifampicin, Ethambutol, and Pyrazinamide
|
Eosinophil counts normalized within a week.
|
Haftu et al, 2020 [15]
|
9/F
|
Right upper quadrant stomach ache, decreased appetite, vomiting, weight
loss, lethargy, and low-grade intermittent fever
|
-Abdominal Ultrasound (US) shows hepatomegaly with aberrant echo pattern
and cystic change
-Liver CT indicates several cystic and tiny daughter cysts as a
connecting hypoechoic mass-like lesion
|
-Leucocytosis with severe eosinophilia with 50%
-The biopsy showed partially encapsulated hepatocyte lobules with many
epithelioid granulomas, large cells, necrosis, and micro abscesses and
chronic inflammatory cells, mostly lymphocytes and eosinophils,
confirming Liver TB.
|
Isoniazid, Rifampicin, Ethambutol, and Pyrazinamide
|
After six months of Anti-Tubercular Therapy (ATT), the patient was
symptom-free, gained 5 kg, and with normal lab findings.
|