Figure 1. Genomic context of the pagR and tktD, tktE genes . PagR activates the transcription of the five-gene operon shown in the figure. The genes encoding the TktC transketolase are the most promoter-distal genes of the operon. tktD = 953 nt,tktE = 830 nt, stm2342 = 1391 nt, stm2343 = 272 nt,stm2344 = 443 nt, pagR = 1019 nt. At present, the location of the promoters is hypothetical. The operon spans the region from 2,257,129 to 2,454, 101 nt (i.e., 3,028 nt) of the S.Typhimurium chromosome. pagR spans the region from 2,457,382 to 2,458401 nt. All genes are at scale.