Siro = sirolimus, VCR = vincristine
*p-value denotes comparison of Siro + Steroids to VCR + steroids only,
Fisher’s exact test
HemR = hematologic response, in patients with KMP only (platelet count
> 100,000/μl x 2 consecutive lab measurements without
transfusion)
RadR = radiologic response (any measurable decrease in tumor size on
radiographic imaging, if tumor measurements were available, the RECIST
criteria for partial response was used)
ClinR = clinical response (resolution of symptoms, functional deficit,
or decrease in size of tumor by visual inspection, even if not a
complete response), radiologic response
TABLE 5 Durability of Response at 3 months and 6 months (Vincristine vs.
Sirolimus)