We report on our experience with the use of HBOT in the treatment of a patient suffering from FM. FM is a very invalidating disease often afflicting young people. The impaired quality of life of these patients has serious ripercussions on public economy. HBOT is a asafe therapy to experiment with FM because it could improve the quality of life of these patients and reduce its economic impact on society. Further studies are needed to improve our understanding of the mechanisms underlying the effects of HBOT and clarify its role in the treatment of these chronic disorders.