frequently reported, they should also be discussed owing to their probability to be further developed. Early in 2014, T. M. Fyles and co-workers applied the intermolecular thioester exchange reaction to fabricate a fuel-driven temporary channel on a bilayer membrane. (Figure 14a) [74] The permeability of the membrane can temporarily enhance upon the addition of chemical fuel. S. J. George et al. demonstrated a solid fuel-driven temporary nanochannel by modifying the wall of the pores of mesoporous silica spheres with pH-responsive groups, such as carboxyl and amino groups. [75] With the aid of the typical OH--ester reaction network (Table 1), the electric field in the 1D nanochannel temporary inversed from positive to negative. As a result, the alkaline chemical fuel would lead a positively charged guest molecule, crystal violet, to be temporarily locked in the 1D channel. Subsequently, with the consumption of the chemical fuel by esterase-catalyzed hydrolysis of ethyl acetate, it was found that the crystal violet was gradually released due to the recovery of the electric field in the 1D channel. (Figure 14b) Considering that temporary regulation of mass transport across the membrane is a vital feature of living organisms, the above works provided a good approach to developing biomimicking membrane materials.