Fig. 3. Treadmill exercise prevented stress-induced anxiety- like
behavior in open field test. ##p<0.01 and###P<0.001 vs. C group;**p<0.01 and ***P<0.05 vs. VD group.
VD-induced recognition memory impairment was ameliorated by treadmill
exercise
As shown
in Fig.
4, the discrimination index of each group were obtained by recognition
memory test. When compared with control rats, the discrimination index
of VD rats was significantly lesser (P<0.05, P<0.01;
Fig. 4B). Conversely, the discrimination index of Exe-VD rats was
significantly greater than VD rats (P<0.05, P<0.01;
Fig. 4B). Thus, these findings thus indicate that treadmill exercise
rescued recognition memory impairment in VD model.