Study; Country; year |
Demographic features |
Past History |
Duration of
illness |
Investigations |
Treatment given |
A case of intractable facial pain secondary to metastatic lung cancer;
Italy;2008 [8]
|
70-year female
|
Non smoker
|
15-month history of constant facial pain.
|
Clinical examination: abnormal breath sounds, loss of sensation on right
side of face.
Chest X-ray: mass in right hilar region
|
Treatment with amitriptyline 40 mg/day and gabapentin (up to 2000
mg/day) was not successful. Pain resolved with radiation therapy and
chemotherapy.
|
Lung cancer presenting with unilateral facial pain: remission after
laryngeal nerve palsy; Italy;2006 [9]
|
39-year female
|
Smoked 1 pack of cigarettes a day for 20 years.
|
2-month history of facial pain on the left side.
|
Clinical examination: Supraclavicular lymphadenopathy
CT scan chest: Mass in left mediastinum.
|
Gabapentin, carbamazepine, and prednisone did not relieve pain. The
patient was treated with chemotherapy: gemcitabine and cisplatin
|
A review of intractable facial pain secondary to underlying lung
neoplasms, USA;2003 [10]
|
63-year-old male
|
65 pack-year history of smoking
|
5 weeks of facial pain
|
ESR elevated
Chest X-ray: right hilar mass.
|
Opioids were unsuccessful. Treated with radiation and
chemotherapy.
|
Facial pain as the presenting symptom of lung carcinoma with normal
chest radiograph; USA,2003 [1]
|
52-year-old man
|
Smoked 3 packs of cigarettes per day for 40
years. Family history of
his father having died of lung cancer.
|
6 months of sharp facial pain
|
WBC count elevated
Chest X-Ray: Right lower lobe mass.
|
Pain did not reduce with NSAIDs and narcotic analgesics. Did not respond
to radiation therapy.
|
Facial pain as the presenting symptom of lung carcinoma with normal
chest radiograph; USA;2003 [1]
|
63-year-old male
|
History of left lower lobectomy for adenocarcinoma-
of the lung. 120 pack-year smoking history.
|
1-month history of progressive pain
|
ESR elevated.
CT chest: subcarinal mass
|
Radiotherapy.
|
Persistent unilateral facial pain in lung cancer patients with
mediastinal nodal involvement; UK;2013 [4]
|
62-year-old man
|
History of wedge resection for lung cancer.
|
After 5 months of resection, he developed facial pain.
|
CT, MRI showed mass in lung and brain
|
Opioids, NSAIDs and neuropathic adjuvants
failed. Palliative radiotherapy and cisplatin – etoposide chemotherapy
relieved the pain.
|
Persistent unilateral facial pain in lung cancer patients with
mediastinal nodal involvement; UK;2013 [4]
|
65-year-old woman
|
No
|
12 months
history of right jaw pain
|
Investigations revealed a T4NXM0
squamous cell carcinoma of the lung. She was
given palliative radiotherapy to the chest, 36 Gy in 12 fractions
|
Amitriptyline gave little pain relief. Palliative radiotherapy to the
chest completely resolved the pain.
|
Facial pain associated with lung cancer: a case report;1983
[2]
|
45-year-old male
|
No
|
4 months of deep, boring pain near maxilla
|
ESR elevated
Chest X ray: mass in right lower lobe
|
Ibuprofen, carbamazepine and diphenhydramine
Hydrochloride did not reduce pain but, aspirin and acetaminophen did.
Pain completely resolved on surgical resection.
|
Unilateral facial pain as the first symptom of lung cancer: are there
diagnostic clues? Belgium;1992 [11]
|
53-year-old
|
Smoker
|
12-month history of facial pain
|
Adenocarcinoma of the right superior lobe was diagnosed
|
Pain was not relieved by analgesics and sphenopalatine
ganglion anaesthesia.
Radiotherapy completely resolved pain.
|
Facial pain as a symptom of nonmetastatic lung cancer; USA;1995
[5]
|
68-year-old woman
|
40 pack year smoking history
|
1-year history of right sided facial pain
|
Clubbing present
Chest X ray: Middle lobe nodular infiltrate
|
The pain did not respond to amitriptyline, narcotic medications,
carbamazepine, phenytoin. Radiotherapy and chemotherapy resolved
pain.
|