Rap protein Phr peptide
Gene cluster localization
Target regulator and action mechanism
RapA PhrA Chromosome Dephosphorylation of Spo0F∼P
RapB PhrC Chromosome Dephosphorylation of Spo0F∼P
RapC PhrC Chromosome Blocks binding of ComA to DNA
RapD Unknown Chromosome Inhibition of ComA activity
RapE PhrE Chromosome Dephosphorylation of Spo0F∼P
RapF PhrF Chromosome Blocks binding of ComA to DNA
RapG PhrG Chromosome Blocks binding of DegU to DNA. Possible inhibition of ComA activity
RapH PhrH Chromosome Dephosphorylation of Spo0F∼P. Blocks binding of ComA to DNA.
RapI PhrI Chromosome Dephosphorylation of Spo0F∼P. Involved in the regulation of mobile genetic elements.
RapJ PhrC Chromosome Possible dephosphorylation of Spo0F∼P
RapK PhrK Chromosome Inhibition of ComA activity
RapLS20
Unknown
Plasmid
Possible dephosphorylation of Spo0F∼P. Regulatory effect on sporulation. Involved in the regulation of mobile genetic elements.
RapP
PhrP (RapP is resistant to PhrP)
Plasmid
Dephosphorylation of Spo0F∼P. Inhibition of ComA activity
RapQ PhrQ Plasmid Inhibition of ComA activity. Possible dephosphorylation of Spo0F∼P. Originally identified in Bacillus amyloliquefaciens.
Rap40 Phr40 Plasmid Unknown
Rap50 Phr50 Plasmid Unknown
Rap60
Phr60
Plasmid
Dephosphorylation of Spo0F∼P. Inhibition of ComA activity