To obtain phenotypic parameters by means of lossy measurement, we proposed a comprehensive and integrated approach to predict different parameters of four varieties of lettuces. By building different prediction models, we required predicted value of five phenotypic parameters of lettuce. Test results indicate that prediction models we have constructed are reliable and feasible. In addition,our methods can be better transferred to the research of other crops, and producers can adjust the growing environment of crops in time, so as to obtain higher yield.