Previous modeling studies indicate that even though marine cloud brightening under a susceptibility-based strategy is effective in reducing the global average surface temperature, it triggers a La Niña-like sea-surface temperature response with cooling mostly confined within lower latitudes. Here we explore a different cloud seeding strategy involving seeding of regions with low susceptibility. Simulations with the Community Earth System Model, version 2 (CESM2) reveal that because the regional forcing is weaker and more widespread, cooling is more evenly distributed over the globe. This new strategy also does not result in the La Niña-like state seen in the other strategies.