We present the first quantitative comparison of source-partitioned CO2 flux measurements with a high-resolution urban fossil CO2 emissions inventory. We use tower-based measurements of CO and 14C to partition net CO2 flux measurements into fossil and biogenic components in a suburban environment. A flux footprint model is used to quantify spatial patterns in fluxes. The partitioned fossil CO2 emissions are compared to a 200-m resolution emissions inventory (Hestia). The results indicate that Hestia and the partitioned flux data agree remarkably well on a seasonal average scale. The Hestia inventory is biased by 3.2% (cold season) and 9.1% (warm season). Their temporal-spatial patterns match closely. In addition, biogenic CO2 uptake is 25% of local fossil emissions during afternoon in the cold season. This work demonstrates the effectiveness of using eddy-covariance flux measurements both for evaluating urban emissions inventories and for quantifying urban ecosystem fluxes.