Objectives: Hypertensive disorders of pregnancy can lead to significant maternal and neonatal complications. No established tests have a high predictive value for PET severity and adverse outcomes. We aimed to investigate the correlation between the aspartate aminotransferase-to-platelet ratio index (APRI) and adverse outcomes in women with PET. Study design: A population-based cohort study at a tertiary medical center was conducted. Population: The study included all women with singletons between the years 2020 and 2022, with PET diagnosis. Women with incomplete records, multiple gestations, and known fetal malformations were excluded. Methods and setting: The median APRI index was used as a cut-off point, allowing us to compare the risk of complications between those with a low and high APRI index. Main outcome measures: Obstetrical and neonatal complications in women with PET in both groups were studied. Results: The study included 513 women with PET who met inclusion criteria. The median APRI index value was used as a cut-off, resulting in 255 women with an APRI index <0.26 and 258 women with an APRI index > 0.26. A higher APRI index was found to be significantly correlated with having a small for gestational age (SGA) newborn and preterm delivery before 34 weeks after controlling for parity, previous cesarean delivery (CD) and maternal age (adjusted OR 1.60, 95% CI 1.01-2.55; p=0.047 and adjusted HR 1.75, 95%CI 1.12-3.09, p=0.047, respectively). Conclusion: In patients with PET, an APRI index > 0.26 is associated with an increased risk for SGA and preterm deliveries. Funding: This study was not funded.

Objective To date, apart from groin and thigh pain, there is a paucity of data regarding the association between transobturator tape (TOT) surgery and lower extremity function. We have aimed to evaluate the association between TOT and various indices of hip joint pain and function. Design Prospective cohort study Settings and Population 37 patients who underwent TOT surgery for the treatments of stress urinary incontinence (SUI). Methods Various tests and questionnaires aimed to assess hip function and surgery outcomes were completed before and after the TOT surgery, at the post-operative clinic. Paired data were compared using the paired sample t-test, after testing for normal distribution. Main Outcome Measures Hip range of motion (ROM), joint function and muscle strength, walking functions, leg length, subjective effect of surgery on patients’ quality of life and the impact of urinary incontinence on daily activities, mental and physical quality of life. Results Decrease in ROM was observed in most cardinal movements of the hip. An increase in leg length following TOT was observed (mean difference in centimeters for both legs 0.87-0.88; p<0.001). An overall trend of decreased strength was noticed, significant for hip adduction. The IIQ-7 and UDI-6 questionnaires demonstrated a significant improvement in urinary function (31.95- and 25.27-point reduction respectively; p<0.05 for both). No significant change was noted in gait function following surgery. Results of the FJS assessment revealed no difference in patient’s awareness of their hip joint. Conclusion Our findings provide support for a yet underestimated association between TOT surgery and hip dysfunction.