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Successful treatment with ivabradine in a β-blocker refractory patient with acute decompensated HFrEF
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  • Tomoko Inoue,
  • Keiji Matsunaga,
  • Waki Kobayashi,
  • Tetsuo Minamino
Tomoko Inoue
Faculty of Medicine, Kagawa University

Corresponding Author:[email protected]

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Keiji Matsunaga
Faculty of Medicine, Kagawa University
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Waki Kobayashi
Faculty of Medicine, Kagawa University
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Tetsuo Minamino
Faculty of Medicine, Kagawa University
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Abstract

Ivabradine is an established treatment for chronic heart failure with reduced ejection fraction (HFrEF) but not for acute heart failure. β-blocker up-titration is often not possible because of its negative inotropic effect (NIE). Ivabradine has no NIE; therefore, it may be preferred over β-blockers in patients with acute decompensated HFrEF.

Peer review status:ACCEPTED

14 Sep 2022Submitted to Clinical Case Reports
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15 Sep 2022Submission Checks Completed
15 Sep 2022Assigned to Editor
17 Sep 2022Reviewer(s) Assigned
20 Oct 2022Review(s) Completed, Editorial Evaluation Pending
21 Oct 2022Editorial Decision: Revise Minor
28 Nov 20221st Revision Received
29 Nov 2022Submission Checks Completed
29 Nov 2022Assigned to Editor
29 Nov 2022Review(s) Completed, Editorial Evaluation Pending
29 Nov 2022Editorial Decision: Revise Minor
13 Dec 20222nd Revision Received
14 Dec 2022Submission Checks Completed
14 Dec 2022Assigned to Editor
14 Dec 2022Review(s) Completed, Editorial Evaluation Pending
03 Jan 2023Editorial Decision: Accept