Study design and setting
This study was performed in conjunction with the PICTURE study
(Pulmonary Magnetic Resonance Imaging of Ex-preterm Children with and
without Bronchopulmonary Dysplasia to Understand Risk of Emphysematous
Changes; clinicaltrials.gov: NCT02921308)13. The
PICTURE study is a multicentre, cross-sectional study which aimed to
evaluate the use of ultra-short echo time MRI to assess lung structure
in children born extremely preterm with and without BPD. This study was
performed at three tertiary pediatric hospitals: the Children’s Hospital
of Eastern Ontario (Ottawa, Ontario), The Hospital for Sick Children
(Toronto, Ontario), and the Centre Hospitalier Universitaire
Sainte-Justine (Montreal, Quebec). Local research ethics board approval
was obtained at each of the participating sites.