AEP amsacrine, etoposide, methylprednisolone
ALL acute lymphoblastic leukemia
AML acute myeloid leukemia
CNS central nervous system
CoALL cooperative study group for childhood acute lymphoblastic leukemia
CPM cyclophosphamide
CTCAE common terminology criteria for adverse events
EOI end of induction
IGH immunoglobulin heavy chain
HR high-risk
HR-I high-risk intensified
HR-IF high-risk induction failure
HSCT hematopoietic stem cell transplantation
IF induction failure
LR low-risk
MRD minimal residual disease
MTX methotrexate
n.q. non quantifiable
pOS probability of overall survival
pEFS probability of event-free survival
PEG-ASP pegylated asparaginase
SAE severe adverse event
SE standard error
TCR T cell receptor