Results
A total of 202 APEs from 51 patients were included in the PK analysis.
Two population PK models were assessed and failed to fit our data. In
all, 109 APEs from 32 patients were included in the clinical analysis.
Factors that significantly impacted clinical outcome were the number of
prior APE and concomitant antibiotics. Clinical success rate for
regimens containing at least one active agent against P.
aeruginosa according to its susceptibility was 67%.