Coexistence of Macrophage Activation Syndrome, Systemic Lupus Erythematosus, and Hepatitis B: A Management Challenge

A document by Oliva Henintsoa RAKOTONIRAINY. Click on the document to view its contents.

ABSTRACTA 24-year-old man was being followed for dilated cardiomyopathy. He presented with bipolar aphthosis and a painless pulsatile abdominal mass. A CT scan showed abdominal aortic and superior mesenteric artery aneurysms and pulmonary embolism. The diagnosis of Behçet’s disease was accepted. The initial course was favorable under corticosteroid therapy.

We report a 24-year-old female patient with a neurological deficit without fever or meningeal syndrome. HIV serology was negative and CD4 count was normal. Cerebrospinal fluid analysis revealed the presence of Cryptococcus neoformans. Neuromeningeal cryptococcosis was suspected. The initial course was favourable with antifungal therapy.