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MANAGEMENT OF SPONTANEOUS PNEUMOTHORAX IN PATIENTS WITH COVID-19
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  • HAKKI ULUTAS,
  • Muhammet Celik,
  • Ilham Gulcek,
  • Muhammed Kalkan,
  • Mehmet Agar,
  • TALAT KILIC,
  • Emine Gulcek
HAKKI ULUTAS
Inonu University School of Medicine

Corresponding Author:[email protected]

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Muhammet Celik
Inonu University Faculty of Medicine Turgut Ozal Medical Center
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Ilham Gulcek
1University of Inonu, Faculty of Medicine,
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Muhammed Kalkan
Inonu University School of Medicine
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Mehmet Agar
Inonu University School of Medicine
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TALAT KILIC
Inonu University Faculty of Medicine
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Emine Gulcek
Inonu University School of Medicine
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Abstract

The coronavirus diseases 2019 (COVID-19) pneumonia may cause cystic features of lung parenchyma which can resolve or progress to larger blebs. Spontaneous pneumothorax (SP) was reported as a complication of COVID-19 with an incidence of 1% in hospitalized patients, in 3% of patients hospitalized with pneumonia, in 6% mechanically ventilated patients and in 1% of decased patients. Pneumothorax was more likely in patients with neutrophilia, severe lung injury and a prolonged clinical course. We present 11 cases of SP managed with chest tube thoracostomy (CTT) or high dose oxygen therapy. Isolated SP was detected in all cases. Eight cases were male and three cases were female. There were bilateral ground-glass opacities or pulmonary infiltrates in the parenchyma of the ten cases. We detected neutrophilia, lymphopenia and increased CRP, Ferritin, LDH, D-Dimer, IL-6 levels in almost all cases. CTT was sufficient to treat pneumothorax in our nine of case. In two cases, pneumothorax healed with high dose oxygen therapy. Favipiravir and antibiotic treatment were given to different ten patients. In our institution, all patients with COVID-19 infection were placed on prophylactic or therapeutic anticoagulation, unless contraindicated. The treatments of patients diagnosed with secondary spontaneous pneumothorax during the pandemic period and those diagnosed with secondary spontaneous pneumothorax in the previous three years were compared with the durations of tube thoracostomy performed in both groups. The increased number of cases of pneumothorax suggests that pneumothorax may be a complication of covid-19 infection. During medical treatment of covid-19, pneumothorax may be the only reason for hospitalization. Although tube thoracostomy is a sufficient treatment option in most cases, clinicians should be aware of the difficulties that may arise in diagnosis and treatment.
18 Oct 2021Published in Interactive CardioVascular and Thoracic Surgery. 10.1093/icvts/ivab280