Neutropenia and anemia secondary to copper deficiency in a child
receiving long term jejunal feeding
- Wing Yan Leung,
- Chi-Chiu So,
- Godfrey Chan,
- Shau yin Ha,
- Alan Chiang,
- Daniel Ka Leung Cheuk
Abstract
Jejunal feeding is increasingly utilized in the pediatric population to
reduce gastroesophageal reflux or aspiration pneumonia. We describe a
pediatric patient who developed persistent neutropenia and anemia
secondary to copper deficiency after more than one year of exclusive
jejunal feeding. Bone marrow aspiration and trephine biopsy showed
vacuolated myeloid and erythroid precursors compatible with copper
deficiency. Short term treatment with mineral mixture powder including
copper reversed the hematological abnormalities. This report highlights
the risk of micronutrient deficiency and the haematological
manifestations as a result of acquired copper deficiency in pediatric
patients receiving long term jejunal feeding.