RESULTS:
The locus FTT_1539 (also spelled FTT1539) of the Francisella tularensis strain Schu S4 genome encodes a protein with 511 amino acid residues, which we will refer to as the FTT_1539 protein. Initial sequence analysis, including Hidden Markov Model (HMM) analysis with Pfam [10], did not indicate homology to any well characterized proteins and thus in the genomics databases it is described as a “conserved hypothetical protein”. Below we present the results of the sequence and structure analyses of this protein.