Discussion:
In this report we describe the largest cohort to date of patients with SDS and COVID-19 infection. Most patients reported a short clinical course with few requiring COVID-19 directed therapy, and only one requiring hospitalization; none experienced significant complications or severe cytopenias. However, these results cannot be generalized to patients with more severe comorbidities. COVID-19 vaccines were well tolerated with only minor expected side effects, suggesting that vaccination should be encouraged according to CDC guidelines during this ongoing global pandemic.
Conflict of Interest: The authors would like to highlight a potential conflict of interest as Drs. Akiko Shimamura and Kasiani Myers work closely with Dr. Peter Newburger on the Severe Congenital Neutropenia International Registry.
Acknowledgments: The authors gratefully acknowledge all patients and families participating in the SDS Registry as well as physician colleagues who referred patients to the Registry.
References: None
Legends: None