Coexistence of Macrophage Activation Syndrome, Systemic Lupus Erythematosus, and Hepatitis B: A Management Challenge

Spontaneous bilateral intra-orbital hematoma is a rare complication of sickle cell disease in children. Imaging examinations are of paramount importance in the diagnosis and condition the management in order to avoid complications that can compromise the visual function prognosis.

A 24-year-old man had vascular purpuric infiltrated, associated elbows and knees’s polyarthralgia, and abdominal pain. The proteinuria was 0.73 g/24 h. Skin histology showed a lymphocytic vasculitis lesion and perivascular infiltrates, without fibrinoid necrosis. The diagnosis IgA vasculitis was made according to the criteria of the ACR and EULAR/PRINTO/PRES.

A 75-year-old man with an aortic bioprosthesis was admitted with polyarthritis in a non-febrile setting. Blood cultures were positive for Listeria monocytogenes. The diagnosis of Listeria endocarditis and spondylodiscitis was evoked. These are two unusual forms of listeriosis.The evolution was favourable after antibiotic therapy.

Rendu Osler's disease is a genetic disease characterized by mucocutaneous and visceral telangiectasias. Rendu Osler's disease was discovered during hypoxemia during an outbreak of SARS-Cov2.This was a 36-year-old woman with exertional dyspnea and severe hypoxemia revealing pulmonary arteriovenous malformations on chest CT scan.