ACKNOWLEDGMENTS
The authors thank the members of the MME Consortium for their contributions to this work over the years and their dedication to global data sharing. K.M.B. was supported by a Canadian Institutes of Health Research Foundation grant FDN-154279 and a Tier 1 Canada Research Chair in Rare Disease Precision Health. A.H. was supported by the​​ National Institutes of Health under awards U54HG006542 and RM1HG010860. H.L.R was supported by the National Human Genome Research Institute of the National Institutes of Health under awards U01HG011755, UM1HG008900, and R01HG009141.