Case Presentation
A 28 years old man, with no systemic disease, presented with recurrent
HSV lesion on the right upper eye lid. He received first dose of chadox1
ncov-19 (AZD1222) vaccine on 20th March 2021 during Iran national
vaccination program. Besides the common post-vaccination signs and
symptoms, two days later, burning pain and blistery skin rashes
developed on the right upper eye lid (Figure 1). Ocular examination was
done by slit-lamp which showed normal findings. Upper eye lid edema
occurred three days later (Figure 2). Along with these findings, patient
remembered an infection with HSV following a trauma to the right eye
with a hand watch in his childhood. According to the patient, he has
experienced periods of cold sore (herpes simplex labialis) after that.
Regarding clinical signs and symptoms and the history of the patient,
treatment was started based on the diagnosis of recurrent HSV lesion of
the upper eye lid. Topical therapy was instructed to the patient
including Eye Drop Sulfacetatamide 10% to treat probable bacterial
conjectivitis and blepharitis because of severe periorbital edema and
Eye Drop Ketotifen and Vitamin A ointment to reduce itching and
irritation. 72 hours later, patient reported blurred vision of the right
eye, which ocular examinations were normal again. Seven days after the
onset of the lesion, signs and symptoms got disappeared. Written
informed consent was obtained from the patient for to the publication of
this report and clinical images.