Abstract

Bronchiectasis and pulmonary fibrosis of the surrounding parenchyma can result from recurrent infection and inflammation. A portion of these patients can present with complete destruction of their lung parenchyma, retraction of the chest cavity and concurrent mediastinal shift. In some cases, lung transplantation is the final option once the reduction of lung capacity becomes clinically detrimental. Concerns with mediastinal shift and chest wall retraction may limit the indication of a double lung transplant in these patients. We report the outcomes as well as preoperative and operative management in two patients with significant lung volume reduction and mediastinal shift due to bronchiectasis of the right lung. Both patients underwent sequential double lung transplantation due to lung failure.