Aim 4: Does executive functioning explain the link between disease-related variables and social adjustment in survivors of ALL?
The path representing the relationship between the antecedent of time off treatment and the mediator of BRIEF-2 score (path a) was not significant, b =-1.25, p =.305. The path representing the relationship between the mediator of BRIEF-2 score and the outcome of BASC-3 Social Withdrawal score (path b) was significant, b =0.42,p =.006. The direct path representing between the antecedent of time off treatment and the outcome of BASC-3 Social Withdrawal score (path c) was not significant, b =1.51, p =.186. The path representing the relationship between the antecedent of time off treatment and the outcome of BASC-3 Social Withdrawal when BRIEF-2 scores were included in the model (path c’) approached significance,b =2.03, p=.056. However, the indirect effect of time off treatment on BASC-3 Social Withdrawal through BRIEF-2 was not significant b =-.53, 95% CI [-1.60, 0.41]. This suggests that executive functioning does not explain the relationship between time off treatment and social adjustment, but rather the relationship between each predictor and social adjustment appear to be direct.