Aim 4: Does executive functioning explain the link between
disease-related variables and social adjustment in survivors of ALL?
The path representing the relationship between the antecedent of time
off treatment and the mediator of BRIEF-2 score (path a) was not
significant, b =-1.25, p =.305. The path representing the
relationship between the mediator of BRIEF-2 score and the outcome of
BASC-3 Social Withdrawal score (path b) was significant, b =0.42,p =.006. The direct path representing between the antecedent of
time off treatment and the outcome of BASC-3 Social Withdrawal score
(path c) was not significant, b =1.51, p =.186. The path
representing the relationship between the antecedent of time off
treatment and the outcome of BASC-3 Social Withdrawal when BRIEF-2
scores were included in the model (path c’) approached significance,b =2.03, p=.056. However, the indirect effect of time off
treatment on BASC-3 Social Withdrawal through BRIEF-2 was not
significant b =-.53, 95% CI [-1.60, 0.41]. This suggests that
executive functioning does not explain the relationship between time off
treatment and social adjustment, but rather the relationship between
each predictor and social adjustment appear to be direct.