Figure 1 : Bone marrow aspirate findings consistent with copper deficiency. (A) Frequent myeloid and erythroid precursor cells with cytoplasmic vacuoles (indicated by arrows) as well as a few nucleated red blood cells with nuclear irregularity in the background (Wright-Giemsa stain, original magnification x 1,000); (B)Occasional ring sideroblasts (indicated by arrows), suggestive of mitochondrial iron deposits (Prussian blue stain, original magnification x 1,000).