Figure 3. (a) Our 2010 model of a Type 2A Aβ42 hexamer; the Aβ1 strand is gold, Aβ2 is red, Aβ3 is blue, the blue star shows the location of the radial axis, the dashed lines and the + in the yellow circle indicates the locations of the perpendicular axes. In some alternative models the Aβ1 segment forms a β-hairpin. (b) Alignment of three Aβ42 segments with α-Syn Nt and NAC segments; all residues of both sequences are included. Residue color code: negatively charged, positively charged, uncharged polar, threonine, apolar and hydrophobic.