Objectives/Aims: Prostatitis is a common entity that is seen in younger than 50 years old men in urology clinics. Subcategory of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) accounts for more than 90% of cases of prostatitis and heterogeneous symptoms cause negative impact on quality of life. Chronic rhinosinusitis (CRS) is a common inflammatory disease of the upper airways and results in a constellation of symptoms that have a significant negative effect on a patient’s quality of life, either. However, both of these entities may share an inflammatory background because of systemic inflammatory responses and endocrine effects of cytokines. In this study, we aimed to find if any symptomatic correlation between CP/CPPS and CRS that can be measurable with National Institute of Health- Chronic Prostatitis Symptom Index (NIH-CPSI) and Sinonasal Outcome Test-22 (SNOT-22) validated symptom scores. Methods: Patients from urology (n:113) and ear-nose-throat (ENT) clinics (n:104) are included in this study. They were questionned with NIH-CPSI and SNOT-22. Also, they were evaluated if there was a correlation between these scores and some parameters (e.g. age, marital status, smoking, masturbation frequency, concomitant inflammatory diseases). Results: As our main result we found out a low-moderate correlation between NIH-CPSI and SNOT-22 scores (r:0.370 for urology, r: 0.466 for ENT patients). Conclusions: In this study we found that, CP/CPPS and CRS have a low correlated relationship symptomatically. We suggest that with further studies and additional data, CP/CPPS and CRS symptom relation might have been connected to a possible main root.