SGS-GPA Investigations
Flexible nasendoscopy & pulmonary function tests were performed in all patients pre-operatively. The average C-M grade on presentation was 1.9 (range 1-3). Computed tomography (CT) or magnetic resonance imaging (MRI) was performed in 18 patients (86%).
ANCA was detected in 12 patients (57%), with the remaining 9 patients treated as ANCA-negative vasculitis. SGS biopsies were taken in 13 patients (62%); the majority showing non-specific inflammation/ fibrosis (11/13), whilst two specimens (2/13) demonstrating GPA through necrosis with focal granulomatosis.