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Long term noninvasive ventilation in children with OSA-I and OSA-II
  • +48
  • Brigitte Fauroux,
  • Chiara Tommesani,
  • Sonia Khirani,
  • Alessandro AMADDEO,
  • Bruno Massenavette,
  • Priscille Bierme,
  • Jessica Taytard,
  • Nathalie STREMLER-LEBEL,
  • Melisande Baravalle-Einaudi,
  • Julie Mazenq,
  • Iulia Ioan,
  • Cyril Schweitzer,
  • Marie-Emilie Lampin,
  • Alexandra Binoche,
  • Clémence Mordacq,
  • Jean Bergounioux,
  • Blaise Mbieleu,
  • Robert Rubinsztajn,
  • elodie sigur,
  • Geraldine Labouret,
  • Aline Genevois,
  • Arnaud Becourt,
  • E. Hullo,
  • ISABELLE PIN,
  • stephane debelleix,
  • François Galodé,
  • Stéphanie Bui,
  • Johan Moreau,
  • marie catherine renoux,
  • Stefan Matecki,
  • Marc Lubrano Lavadera,
  • Rachel Heyman,
  • Michael Pomedio,
  • Laurence Le Clainche Viala,
  • Plamen Bokov,
  • Alexandra Masson,
  • Pauline Hangard,
  • Céline Menetrey,
  • Mikael Jokic,
  • Elsa Gachelin,
  • Caroline Perisson,
  • Anne Pervillé,
  • Agnès Fina,
  • L. GIOVANNINI-CHAMI,
  • Emmanuelle Fleurence,
  • Audrey Barzic,
  • Audrey Breining,
  • Morgane Ollivier,
  • Guillaume Labbé,
  • Laurianne Coutier,
  • Guillaume Aubertin
Brigitte Fauroux
Hopital Universitaire Necker-Enfants Malades

Corresponding Author:[email protected]

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Chiara Tommesani
Universita degli Studi di Milano-Bicocca Scuole di Specializzazione
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Sonia Khirani
Hopital Universitaire Necker-Enfants Malades
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Alessandro AMADDEO
Hopital Universitaire Necker-Enfants Malades
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Bruno Massenavette
Hospices Civils de Lyon
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Priscille Bierme
Hospices Civils de Lyon
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Jessica Taytard
Centre de Recherche Saint Antoine
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Nathalie STREMLER-LEBEL
Assistance Publique Hopitaux de Marseille
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Melisande Baravalle-Einaudi
Assistance Publique Hopitaux de Marseille
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Julie Mazenq
Assistance Publique Hopitaux de Marseille
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Iulia Ioan
Universite de Lorraine IUT Nancy-Charlemagne
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Cyril Schweitzer
Universite de Lorraine IUT Nancy-Charlemagne
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Marie-Emilie Lampin
Centre Hospitalier Universitaire de Lille Institut Coeur Poumon
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Alexandra Binoche
Centre Hospitalier Universitaire de Lille Institut Coeur Poumon
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Clémence Mordacq
Centre Hospitalier Universitaire de Lille
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Jean Bergounioux
Hopital Raymond-Poincare Unite de Nutrition
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Blaise Mbieleu
Hopital Raymond-Poincare Unite de Nutrition
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Robert Rubinsztajn
Hopital Universitaire Necker-Enfants Malades
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elodie sigur
Hopital des Enfants
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Geraldine Labouret
Hopital des Enfants
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Aline Genevois
Hopital des Enfants
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Arnaud Becourt
Centre Hospitalier Universitaire Amiens-Picardie Centre Saint-Victor
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E. Hullo
Centre Hospitalier Universitaire Grenoble Alpes Pole Couple Enfant
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ISABELLE PIN
Centre Hospitalier Universitaire Grenoble Alpes Pole Couple Enfant
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stephane debelleix
Centre Hospitalier Universitaire de Bordeaux Groupe hospitalier Pellegrin Hopital des Enfants
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François Galodé
Centre Hospitalier Universitaire de Bordeaux Groupe hospitalier Pellegrin Hopital des Enfants
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Stéphanie Bui
Centre Hospitalier Universitaire de Bordeaux Groupe hospitalier Pellegrin Hopital des Enfants
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Johan Moreau
Universite de Montpellier Faculte de Medecine Montpellier-Nimes
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marie catherine renoux
Universite de Montpellier Faculte de Medecine Montpellier-Nimes
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Stefan Matecki
Universite de Montpellier Faculte de Medecine Montpellier-Nimes
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Marc Lubrano Lavadera
Hopital Charles-Nicolle Clinique Dermatologique
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Rachel Heyman
Universite de Rennes Institut universitaire de technologie de Rennes
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Michael Pomedio
Centre Hospitalier Universitaire de Reims
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Laurence Le Clainche Viala
Hopital Universitaire Mere-enfant Robert-Debre
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Plamen Bokov
Hopital Universitaire Mere-enfant Robert-Debre
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Alexandra Masson
Hopital de la mere et de l'enfant
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Pauline Hangard
Hopital de la mere et de l'enfant
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Céline Menetrey
Hopital de la mere et de l'enfant
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Mikael Jokic
Universite de Caen Normandie UFR Sante
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Elsa Gachelin
Centre Hospitalier Universitaire de La Reunion
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Caroline Perisson
Centre Hospitalier Universitaire de La Reunion Sites Sud
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Anne Pervillé
Universite de la Reunion Bibliotheque Universitaire Saint-Denis Sciences
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Agnès Fina
Hopitaux Pediatriques de Nice CHU-LENVAL
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L. GIOVANNINI-CHAMI
Hopitaux Pediatriques de Nice CHU-LENVAL
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Emmanuelle Fleurence
Centre Hospitalier Universitaire de Nantes Pole hospitalo-universitaire 5 femme enfant adolescent
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Audrey Barzic
Centre Hospitalier Regional et Universitaire de Brest
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Audrey Breining
Universite de Strasbourg Telecom Physique Strasbourg
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Morgane Ollivier
Centre Hospitalier Universitaire d'Angers
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Guillaume Labbé
Centre Hospitalier Universitaire de Clermont-Ferrand
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Laurianne Coutier
Hospices Civils de Lyon
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Guillaume Aubertin
Centre de Recherche Saint Antoine
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Abstract

Objective The aim of the study was to describe the characteristics of otherwise healthy children with obstructive sleep apnea (OSA; OSA-I) and children with OSA and obesity (OSA-II) treated with long term continuous positive airway pressure (CPAP) or noninvasive ventilation (NIV) in 2019 in France. Design National cross-sectional survey. Patients Children with OSA-I and OSA-II. Main outcome measures Initiation criteria, age, adherence, equipment and settings Results Patients with OSA-I and OSA-II represented 6% (n=84, 71% males) and 10% (n=144, 72% males) of the national cohort, respectively. The apnea-hypopnea index (63% vs 76%), alone or combined with nocturnal gas exchange (25% vs 21%, for OSA-II and OSA-I patients respectively) were used as initiation criteria of CPAP/NIV. OSA-II patients were older at CPAP/NIV initiation (mean age 11.0±4.0 vs 6.8±4.5 years, p<0.001) and were treated for a longer time (2.3±2.6 vs 1.3±1.5 years, p=0.008) than OSA-I patients. NIV was used in 6% of OSA-I patients and 13% of OSA-II patients (p=0.142). Nasal mask was the most used interface in both groups. Mean CPAP level was higher in OSA-II patients as compared to OSA-I patients (8.7±2.0 vs 7.7±2.4 cmH 2O, p=0.02). Objective compliance was comparable (mean use 6.8±2.6 vs 5.9±3.0 hours/night in OSA-I and OSA-II, respectively, p=0.054). Conclusion Six and 10% of children treated with long term CPAP/NIV in France in 2019 had OSA-I and OSA-II, respectively. Both groups were preferentially treated with CPAP and were comparable except for age, with OSA-II patients being older.
21 Mar 2024Submitted to Pediatric Pulmonology
21 Mar 2024Submission Checks Completed
21 Mar 2024Assigned to Editor
21 Mar 2024Review(s) Completed, Editorial Evaluation Pending
22 Mar 2024Reviewer(s) Assigned