Figure legends
Figure 1. Flow chart of study participant selection.
CMA, cow’s milk allergy; CM-OIT, cow’s milk oral immunotherapy
Figure 2. Kaplan–Meier analysis of the tolerance acquisition
rate in children aged 6–12 years with CMA. Patients enrolled in oral
immunotherapy after the age of 6 years were considered as having
continued elimination of cow’s milk.
CMA, cow’s milk allergy
Figure 3. Kaplan–Meier
curves showing CMA tolerance from ages 6–12 years. (A) Grouped by the
optimal cutoff value of CM-sIgE levels, as determined by the receiver
operating characteristic curve. (B) Grouped by complete elimination of
CM by the age of 6 years. (C) Grouped by anaphylaxis to CM prior to the
age of 6 years. (D) Grouped by combinations of the two factors, complete
CM elimination from the diet and previous anaphylaxis to CM at the age
of 6 years. Two of 45 children (4%) with complete CM elimination and
previous anaphylaxis, 10 of 36 children (28%) with complete CM
elimination but without previous anaphylaxis, 10 of 14 children (71%)
with partial CM elimination and previous anaphylaxis, and 24 of 28
children (86%) with partial CM elimination but without previous
anaphylaxis acquired tolerance (A-D) Groups are significantly different
(p < 0.001, log-rank test).
CM, cow’s milk; CM-sIgE, CM-specific immunoglobulin E; CMA, CM allergy