Definitions
IgE-mediated CMA was diagnosed by either sensitization to CM and a history of a convincing immediate-type allergic reaction to CM or failure in a CM oral food challenge (OFC). Tolerance acquisition was defined as either passing an OFC of consuming 200 mL of unheated CM or CM of any quantity without allergic symptoms. Persistent CMA was defined as fulfilling neither of these criteria by the age of 12 years. Partial elimination was defined as being able to consume < 200 mL of CM without allergic symptoms. Children with CMA who were enrolled in CM oral immunotherapy (OIT) after 6 years of age were defined as having persistent CMA.