Genes commonly observed in the two multiplex stuttering
families
To determine the genes causing stuttering, the expansive list of genes
with variations, that was exclusive to the affected individuals in each
family was compared (276 genes in STU-66 family and 294 in STU-65).
Seven genes (SLC36A1, C1orf167, SYNC, TM4SF1, MUC6, SPTBN5 andMSRB1) were found to be common to both families, irrespective of
the variants identified (figure A4). All the affected members harbored
multiple variants in each of these seven genes.